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Pfizer Inc. engages in the discovery, development and manufacture of healthcare products, specialising in medicines, vaccines and consumer healthcare. It operates through the Pfizer Innovative Health (IH) and Pfizer Essential Health (EH) segments. The IH segment focuses on the development and commercialisation medicines and vaccines for internal medicine, oncology, inflammation and immunology, rare disease and consumer healthcare. The EH segment is involved in development and supply of branded generics, generic sterile injectable products, biosimilars and select branded products including anti-infectives. The company was founded by Charles Pfizer Sr. and Charles Erhart in 1849 and is headquartered in New York, NY.